The Liverpool manager aims to repeat the semi-final triumph he masterminded almost exactly two years ago on the way to the club's fifth European Cup final victory.
But by highlighting the Blues' desire to win the world's major club trophy, he has subtly implied that they are likely to fail to complete a hat-trick of Premiership crowns following their critical draw at Newcastle on Sunday.
That result meant the current champions failed to take advantage of Manchester United's slip-up 24 hours earlier against Middlesbrough, which looked to have gifted a route to the title for Chelsea.
But now Benitez believes that Jose Mourinho's objectives will have shifted towards the one trophy that means more than anything else to the west Londoners.
He said: "Can Chelsea win the title now? I do not know, they will go right to the end, that is clear. But Manchester United have done a great job, a fantastic season.
"The Champions League will be Chelsea's priority - they will know that it is the major competition now for them and they will be really focused on that.
"The Premiership title is important to them certainly, they have won the last two, but now I feel they will thinking more about the Champions League."
And Benitez revealed that his squad are showing the hunger for more success of their own.
He said: "I believe the present at Liverpool is really good and the future can be even better with new investment.
"I can tell you the players are as hungry for success now as they were two years ago."
By outlining the dilemma now facing Mourinho, Benitez also suggests that Chelsea will now fail in both of their main objectives for the season, the title and the European crown.
Liverpool have won three of the last four meetings between the clubs and know that they have a big advantage with the second leg at Anfield, a repeat of the cauldron of hate Chelsea had to face two years when a fearful barrage of noise contributed to Liverpool's 1-0 victory that sent them to Istanbul.
Benitez said: "We are boosted by the fact that we beat them in our last meeting at Anfield, and we know that the atmosphere and support we can generate there is very important for us.
"I suppose I would like to be in Chelsea's position only because it means trophies would have been won.
"But if you ask me whether I would want to swap this city, my team, my club, our stadium and supporters then the answer is no."
Benitez will have a near fully fit squad to chose from, with Steve Finnan recovered from a neck problem and Jamie Carragher about to equal Ian Callaghan's club record of 89 European appearances.
And having already produced significant away victories over PSV Eindhoven and Barcelona in the previous knock-out rounds this term, Benitez believes Liverpool can do it again.
He said: "Our aim is to approach this game in the same way that we did against Barcelona, we want to win and we want to score.
"It may be more difficult because Chelsea do not concede many goals.
"But we will be organised and aim to score a goal that will give us so much more to utilise for the second leg.
"Away goals are so important, we always try to go forward to do that (score). It will be more difficult at Chelsea but we will be trying to do that."
Benitez did nothing to dispel the theory that Chelsea are beginning to struggle under their intense workload.
They will be without the suspended Michael Essien tomorrow and there are doubts over Michael Ballack and Ricardo Carvalho.
Benitez said: "They have had some tough games, playing on Sunday at Newcastle. But it has happened to us this season, having to play games very soon after European matches with lunchtime starts - these things even themselves out.
"But it was important for us to rest players on Saturday against Wigan, particularly Steven Gerrard. And it also gave us the chance to give other players a run-out.
"All these things are positive and Gerrard will be that little bit better and sharper now.
"I have confidence we will score, it is everything we are planning in our approach.
"We have different players than the last time but we have gained a lot of experience playing in Europe over the last two years."
He added: "They may talk about winning other trophies and they have a very good squad for competing at this stage of the season for trophies.
"But their priority now will be the Champions League, I am sure of that.
"We go to Stamford Bridge intent on winning. We have done that both against Barcelona and PSV Eindhoven in the previous knock-out rounds.
"I know this could easily be a Premiership game, but I would prefer to approach it like a typical European match because normally we win those a lot, at home and away. It is a situation I like better.
"But we do not under-estimate Chelsea. They are a very, very good side and have proved that by winning the title in the last two seasons - that is more my concern than anything they may be thinking about how we beat them at this stage in 2005.
"We are a better team than two years ago, maybe they are too, but for us we have more experience and we think we can do it again."