The 26-year-old joined the Trotters from Liverpool two years ago but has reportedly been considering his future at the Reebok since the departure of Sam Allardyce, who has apparently made moves to lure him to Newcastle.
And the Senegal frontman is tempted by the prospect of helping Lyon's bid for a seventh straight Ligue 1 title.
His agent Alexandre Krstic said: "He is interested in Lyon. They are a big European club playing Champions League football.
"There's been contact with other Premier League sides, but Bolton have to accept (a bid) to talk to them."